Frank Oppenheimer
- Birth Date
- 8/14/1912 - 2/3/1985
- Birth Place
- New York City, New York, USA
- Known For
- Acting

Frank Oppenheimer was an American particle physicist, cattle rancher, professor of physics at the University of Colorado, and the founder of the Exploratorium in San Francisco. A younger brother of renowned physicist J. Robert Oppenheimer, Frank Oppenheimer conducted research on aspects of nuclear physics during the time of the Manhattan Project, and made contributions to uranium enrichment.
