Melissa De Sousa
- Birth Date
- 9/25/1967
- Birth Place
- New York City, New York, USA
- Known For
- Acting
Melissa De Sousa is an actress best known for her role as Shelby in the 1999 romantic comedy-drama film The Best Man, its 2013 sequel The Best Man Holiday, Gabriella Jimenez in BET's Reed Between the Lines, and Ana Lopez in Black Lightning.
